CHICAGO (CBS) -- Lysosomes – membrane-bound structures within each cell of humans and all animals – are sometimes known as the cells' "garbage disposals" or "cellular janitors." The structures are ...

Lysosomes are membrane-bound organelles in cells that act as recycling centers—breaking down waste materials, damaged organelles, and unwanted molecules using powerful digestive enzymes. Lysosomes ...

Stanford researchers constructed an atlas of the proteins found in the lysosome across different brain cell types, a recently published paper reported. Lysosomes are cell organelles that play ...

Transmission electron microscopic image of an isolate from the first U.S. case of COVID-19, formerly known as 2019-nCoV. The spherical viral particles, colorized blue, contain cross-section through ...

Lysosomes were once viewed mainly as cellular waste disposers, but are now recognized as key hubs for nutrient sensing and metabolic signaling. Still, what lysosomes contribute metabolically inside ...

The rap sheet for β-CTF is growing longer. The C-terminal fragment, produced when β-secretase cleaves APP, binds to—and blocks assembly of—vacuolar ATPase, a proton pump that fuels acidification of ...

Common variants in the phosphoinositol phosphatase INPP5D are linked to an increased risk of late-onset Alzheimer’s disease, but no one is quite sure why. Recent work suggests that depleting INPP5D in ...