Although the pathophysiology of mesangial cells has long been considered to be the major factor in the development of glomerulosclerosis in type 1 or type 2 diabetes, more recent evidence suggests ...

BioWorld - Tuesday, November 11, 2025 Breaking News: Trump administration impacts continue to roil the life sciences sector See today's BioWorld Science Home » Podocyte-directed gene therapy in ...

OTU deubiquitinase 5 (OTUD5) is a deubiquitinating enzyme that has been shown to play a key role in mediating innate immunity and inflammation development, and which is also involved in various ...

Acute kidney injury (AKI) often occurs as a result of ischemia, which is a condition in which blood flow to part of the body is restricted, depriving tissues of oxygen and nutrients. This damage is ...

The kidneys are vital organs that sustain life by filtering the blood and producing urine. This filtration process takes place in specialized structures called glomeruli, where podocytes play a ...

A single podocyte was reconstructed in three dimensions based on serial glomerular section images obtained by array tomography. The three-dimensional reconstruction enabled quantitative volume ...

Associate Professor in Microvascular Medicine, Rebecca Foster, explores therapeutic approaches to improve kidney health for ...