Discovery reshapes understanding of how tumor cells repair broken DNA, pointing toward more precise cancer therapies.

A cancer drug target already being investigated in clinical trials turns out to be doing something even more consequential ...

When an SSB appears, polymerase epsilon approaches the nick before retracing its steps thanks to its exonuclease, allowing fork reversal to take place. The nick is repaired as an SSB, and replication ...

The Smolka Lab, led by Prof. Marcus Smolka, molecular biology and genetics, recently published a study shedding light on a novel pathway that explains how cancer cells can become resistant to ...

Embryonic stem (ES) cells are pluripotent stem cells that can produce all cell types of an organism. ES cells proliferate rapidly and have been thought to experience high levels of intrinsic ...

Researchers from Tokyo Metropolitan University have identified key factors in the mechanism behind DNA repair in our bodies. For the first time, they showed that the "proofreading" portion of the DNA ...

Error-prone DNA replication and repair may lead to mutations and cancer in individuals who inherit a mutant copy of the BRCA1 gene, according to a new study by Weill Cornell Medicine investigators.

BAGNEUX, France--(BUSINESS WIRE)--Regulatory News: Genomic Vision (the “Company” - FR0011799907 – GV) (Paris:GV), a biotechnology company that develops tools and services dedicated to the analysis and ...