Frontiers

Immunometabolism and Molecular Signaling in Systemic Inflammation: Connecting Acute Stress to Chronic Diseases

Systemic inflammation research occupies a pivotal position at the intersection of immunology, metabolism, and disease pathogenesis. Recent advances have ...
Science Daily

B cells drive responses of other immune cells, and can be modified to prevent Multiple Sclerosis symptoms

B cells can control responses of myeloid cells through the release of particular cytokines (small proteins that control the growth and activity of cells in the immune system), challenging the ...
IEEE

Effects of Thermo-Oxidative Aging on the Dielectric Property and Electrical Breakdown of Epoxy Resin Using in High-Voltage Equipment

Abstract: In this article, the effects of thermo-oxidative aging on the dielectric properties of epoxy resin are investigated at 180 °C under different durations. In the early stage of aging (0–168 h) ...
BioTechniques

How GLP-1 agonists affect gene expression and promote pancreatic health

Researchers have found a protein that connects GLP-1 agonist drugs to long-term, broad genomic responses that can promote pancreatic health and resilience. GLP-1s are building a reputation as ‘wonder ...
eLife

Elucidating the kinetic and thermodynamic insight into regulation of glycolysis by lactate dehydrogenase and its impact on tricarboxylic acid cycle and oxidative ...

This study presents an assessment of the effect of lactate dehydrogenase (LDH) inhibition on the activity of glycolysis and tricarboxylic acid cycle. The data were collected and analyzed using solid ...
Medical Xpress

Molecular Function: Oxidative Phosphorylation

Ultrafine particles, UFPs, the smallest contributors to air pollution, hinder the function of mitochondria in human olfactory mucosa cells, a new study shows. Led by the University of Eastern Finland, ...
Psychology Today

Oxidative Stress: What a Headache!

Everybody knows that stress gives you a headache. Everybody knows that a lack of sleep gives you a headache. In fact, everybody knows that drinking wine, skipping a meal, and studying too hard for a ...
eLife

Dual-modal metabolic analysis reveals hypothermia-reversible uncoupling of oxidative phosphorylation in neonatal brain hypoxia-ischemia

This is an important study that utilized in vivo optical measurements of the cortical metabolic rate of O2 and blood flow, as well as measurements in isolated mitochondria to assess the uncoupling of ...
News Medical

Johns Hopkins study reveals enzyme that shields neurons from oxidative stress

New research from Johns Hopkins Medicine shows that the enzyme biliverdin reductase A (BVRA) plays a direct protective role against oxidative stress in neurons, independent of its role producing the ...
ascopubs.org

Integrated analysis of bulk and single-cell RNA sequencing data to identify an oxidative phosphorylation-based prognostic signature for lung adenocarcinoma.

Diagnostic performance of SHOX2 and RASSF1A gene methylation assays in malignant pleural effusion: A systematic review and meta-analysis. This is an ASCO Meeting Abstract from the 2025 ASCO Annual ...
ascopubs.org

Clear and non-clear cell renal cell carcinomas and the ability to engage in oxidative phosphorylation.

Neoadjuvant lenvatinib plus pembrolizumab for resectable clear-cell renal cell carcinoma (PELUR): A prospective phase 2 study. This is an ASCO Meeting Abstract from the 2025 ASCO Annual Meeting I.