EurekAlert!

Characteristics of CD4+T-cell reduction and pulmonary infections in critically ill immunocompromised patients

In this study, we revealed the pulmonary pathogen profiles of immunosuppressed ICU patients based on CD4+T-cell counts: the ...
EurekAlert!

Evolutionary conservation of CD4 and LAG-3 and their cytoplasmic tail motifs with opposing immune functions: do we finally understand LAG-3?

Conservation of their respective cytoplasmic tail motifs, CxC/H in the case of CD4 and an ITIM-like motif in the case of LAG-3, supports that competition between CD4 and LAG-3 for binding of kinase ...
Medscape

Low CD4 Count Tied to Cervical Cancer Risk in HIV Infection

A lower CD4 count is associated with a higher risk for cervical carcinoma in situ and cervical cancer in women with HIV ...
The American Journal of Managed Care

CD4/CD8 Ratio a Useful Predictor of Mortality in Patients Living With HIV

A review found that CD4/CD8 ratio could be used as a prognostic marker for mortality in patients with HIV, though future studies need to be done to confirm these findings. Clinical practices can ...