This review argues that neurodegeneration is shaped not only by toxic protein buildup but also by immune signaling, with ...

Researchers from City of Hope(R) , one of the largest and most advanced cancer research and treatment organizations in the United Sta ...

The ongoing global climate crisis is characterized by rising mean water temperatures, thermal stress, ocean acidification, and fluctuating dissolved oxygen ...

Physicians and scientists from the UCLA Health Jonsson Comprehensive Cancer Center will present new research at the American Association for Cancer Research (AACR) Annual Meeting, highlighting ...

Multiple sclerosis (MS) is a debilitating neurological disorder caused by malfunctioning immune responses that target the brain and spinal cord of the central nervous system (CNS). New research led by ...

LAG-3 is identified as a potential biomarker for SCLC, aiding in patient stratification for ICI therapy. Higher LAG-3 expression in SCLC correlates with improved survival and increased immune activity ...

SCLC has a poor prognosis with less than 7% 5-year survival, and limited surgical specimens hinder understanding. FAK inhibition is identified as a potential therapeutic target due to high-frequency ...

Disturbance in protein synthesis and degradation plays a crucial role in various biological and pathological processes. E3 ubiquitin ligase substrate–binding adaptor SPOP (speckle-type POZ [poxvirus ...

While cardiovascular diseases continue to be the foremost cause of death worldwide, heart failure constitutes a major segment responsible for these mortalities. Heart failure results from exhausted ...

A recent article in Nature Communications describes a nanovaccine platform designed to support the development of personalized cancer vaccines. This approach uses tumor cell membranes enriched with ...

The study by Li et al. provides fundamental findings supported by convincing evidence that they defined cellular reprogramming of androgen receptor in neuroendocrine prostate cancer (NEPC). The ...