Researchers Expose Hidden Chemistry of “Ore-Forming” Elements in Biology

On the far right side of the periodic table, just beneath oxygen, sits a lesser-known group of elements called the chalcogens ...
BioTechniques

How GLP-1 agonists affect gene expression and promote pancreatic health

Researchers have found a protein that connects GLP-1 agonist drugs to long-term, broad genomic responses that can promote pancreatic health and resilience. GLP-1s are building a reputation as ‘wonder ...
eLife

Elucidating the kinetic and thermodynamic insight into regulation of glycolysis by lactate dehydrogenase and its impact on tricarboxylic acid cycle and oxidative ...

This study presents an assessment of the effect of lactate dehydrogenase (LDH) inhibition on the activity of glycolysis and tricarboxylic acid cycle. The data were collected and analyzed using solid ...
Medical Xpress

Molecular Function: Oxidative Phosphorylation

Ultrafine particles, UFPs, the smallest contributors to air pollution, hinder the function of mitochondria in human olfactory mucosa cells, a new study shows. Led by the University of Eastern Finland, ...
eLife

Dual-modal metabolic analysis reveals hypothermia-reversible uncoupling of oxidative phosphorylation in neonatal brain hypoxia-ischemia

This is an important study that utilized in vivo optical measurements of the cortical metabolic rate of O2 and blood flow, as well as measurements in isolated mitochondria to assess the uncoupling of ...
News Medical

Johns Hopkins study reveals enzyme that shields neurons from oxidative stress

New research from Johns Hopkins Medicine shows that the enzyme biliverdin reductase A (BVRA) plays a direct protective role against oxidative stress in neurons, independent of its role producing the ...
The American Journal of Managed Care

Higher Oxidative Balance Score Linked to Lower Systemic Inflammation, Study Finds

A negative correlation exists between oxidative balance score (OBS) and systemic immune-inflammation index (SII), indicating higher antioxidant capacity reduces inflammation. OBS is calculated from ...
ascopubs.org

Integrated analysis of bulk and single-cell RNA sequencing data to identify an oxidative phosphorylation-based prognostic signature for lung adenocarcinoma.

Diagnostic performance of SHOX2 and RASSF1A gene methylation assays in malignant pleural effusion: A systematic review and meta-analysis. This is an ASCO Meeting Abstract from the 2025 ASCO Annual ...
ascopubs.org

Clear and non-clear cell renal cell carcinomas and the ability to engage in oxidative phosphorylation.

Neoadjuvant lenvatinib plus pembrolizumab for resectable clear-cell renal cell carcinoma (PELUR): A prospective phase 2 study. This is an ASCO Meeting Abstract from the 2025 ASCO Annual Meeting I.
Scientific Research Publishing

Emre, M., Cetiner, S., Zencir, S., Unlukurt, I., Kahraman, I. and Topcu, Z. (2010) Oxidative Stress and Apoptosis in Relation to Exposure to Magnetic Field. Cell Biochemistry ...

ABSTRACT: The increasing prevalence of artificial electromagnetic radiation (EMR) sources has raised concerns about their potential impact on biological systems, particularly through modifications of ...
Frontiers

Unraveling the interplay between sleep, redox metabolism, and aging: implications for brain health and longevity

The relationship between sleep and metabolism has emerged as a critical factor in aging and age-related diseases, including Alzheimer’s disease and dementia. Mitochondrial oxidative phosphorylation, ...